How does Body Roundness Index correlate with mortality risk ?

Created/Updated: #feb2025

Research by : Xiaoqian Zhang, MD; Ning Ma, MD; et al.
Summary by: GPT-4o
Edited and Curated by : Dr. Om J Lakhani
Useful mini-application: Body Roundness Index Calculator
Patient information: The better marker for Obesity- The BRI
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Summary of the article

1. Title of the article:
Body Roundness Index and All-Cause Mortality Among US Adults

2. First two Authors followed by et al:
Xiaoqian Zhang, MD; Ning Ma, MD; et al.

3. One line summary of the article:
The study highlights a U-shaped association between Body Roundness Index (BRI) and all-cause mortality among US adults, showing both low and high BRI values increase mortality risk.

4. Six key points from the article:

  1. Increasing BRI Trend: Between 1999 and 2018, the mean BRI increased from 4.80 to 5.62 with a biennial change of 0.95%.
  2. U-Shaped Mortality Risk: Both low BRI (<3.4) and high BRI (>6.9) were associated with significantly higher mortality risk compared to a middle BRI range (4.5–5.5).
  3. Higher Risk for High BRI: Individuals with BRI ≥6.9 had a 49% increased mortality risk (HR 1.49; 95% CI, 1.31–1.70).
  4. Demographic Variations: BRI trends were more pronounced among women, elderly individuals, and Mexican Americans.
  5. Visceral Fat Representation: BRI was superior to BMI in reflecting visceral adiposity, which is more associated with mortality.
  6. Practical Utility: BRI shows potential as a non-invasive and comprehensive screening tool for mortality risk prediction in clinical and public health settings.

5. Practical take-home message:
The Body Roundness Index (BRI) is an effective tool to assess visceral obesity and mortality risk. Clinicians should consider BRI alongside traditional measures like BMI for a more accurate evaluation of obesity-related risks.

6. Citation for the article in Vancouver format:
Zhang X, Ma N, Lin Q, Chen K, Zheng F, Wu J, et al. Body Roundness Index and All-Cause Mortality Among US Adults. JAMA Netw Open. 2024;7(6):e2415051. doi:10.1001/jamanetworkopen.2024.15051


Body Roundness Index (BRI): An Overview

BRI Calculation

Required Measurements:

i. Waist circumference
ii. Height

BRI Interpretation

Health Risks:

Advantages of BRI

Limitations of BRI

Conclusion

Mini-Application