- Credits
- Section Writer: Dr. Om J Lakhani
- Section Editor: Dr. Om J Lakhani
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Q. What are the ways in which ovulation can be detected?
- To detect impending ovulation
- Urinary LH detection kit or serum LH
- Basal body temperature measurement
- Ultrasound
- Change in cervical mucus – spinbarkitt
- To detect ovulatory cycles
- Menstrual cycle period and regularity – 28-35 days with normal regulatory- more likely to be ovulatory
- Molimina symptoms
- Luteal phase progesterone
- Detect CL and endometrium on ultrasound
- Endometrial biopsy
- To detect impending ovulation
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Q. What length of cycles is generally ovulatory?
- Menstrual cycles between 25-35 days are generally ovulatory
- Both shorter and longer cycles suggest anovulation
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Q. What are the clinical symptoms that suggest ovulation ?
- Midcycle
- Cervical mucus becomes thin
- Mittelschmerz (midcycle bleeding)
- End of cycle – premenstrual (molimina symptoms)
- 1 bloating
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- Breast tenderness
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- Fluid retention
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- Mood changes
- Presence of molimina symptoms suggest ovulation
- Midcycle
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Q. When does the rise in basal body temperature take place?
- Occurs 1-5 days after LH surge (generally 1-4 days after ovulation)
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Q. What is the fundamental of basal body temperature measurement?
- Progesterone in the luteal phase affects the hypothalamus and increases basal body temperature
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Q. Describe the process of basal body temperature measurement?
- Women measures the temperature by keeping the thermometer beneath the tongue every day before getting out of the bed
- During the luteal phase, the temperature increase by 0.5 F compared to the follicular phase
- It begins to rise 1-2 days after LH surge and remains high for ten days
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Q. If the woman does not give the above history of normal ovulatory cycles, then what is done?
- Do a mid-lueteal phase progesterone
- It is done seven days before the expected date of menses (21st day of cycle)
- If the level is >3 pg/ml- it suggests that ovulation has occurred [1]
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Q. Is this test always done on the 21st day of the cycle?
- No
- It is done seven days before the expected menstrual period
- For women with a cycle length of 28 days, it is done on the 21st day
- With the cycle of the length of 30 days, it is done on the 23rd day and so on
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Q. What are the means of identifying the fertile period?
- Calendar method
- Basal body temperature measurement
- LH surge using urinary LH detection kit
- Recording the change in cervical mucous
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Q. How is the fertile period calculated?
- The Fertile period is calculated by subtracting 14 days from the total cycle length of the shortest and longest periods
- Couple is counseled for intercourse at least every other day during the fertile period
- For example, if a person has a cycle length of 30 to 35 days – fertile days would be days 16 to 21 of the menstrual cycle (30-14 and 35-14)
- LH surge occurs five days before ovulation
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Q. What is the time difference between LH surge in serum and urine?
- LH surge in blood precedes urinary LH surge by 12 hours
- This can be detected using home LH detection kits
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Q. When does ovulation take place after LH surge?
- Ovulation occurs about 14-48 hours after LH generally
- Couples are advised that maximum fertility is for two days after LH surge is detected by the Kit
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Q. How can ultrasound help in the diagnosis of ovulation?
- It is most helpful if used serially
- Both TAS and TVS can be used. TVS is preferred
- Ovulation can be predicted by seeing a large preovulatory follicle of 20-25 mm in size before rupture
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Q. How does the ultrasound appearance of endometrium suggest the phase of menses?
- Follicular phase- the ultrasound shows thick proliferative endometrium
- Luteal phase shows- bright echogenic endometrium
Wathen NC, Perry L, Lilford RJ, Chard T. Interpretation of single progesterone measurement in diagnosis of anovulation and defective luteal phase: observations on analysis of the normal range. Br Med J (Clin Res Ed). 1984 Jan 7;288(6410):7-9. DOI: 10.1136/bmj.288.6410.7. PMID: 6418326; PMCID: PMC1444184 ↩︎